MIMS Education

Managing COVID-19 Patients with Renal Insufficiency, Multiple Comorbidities, or Compromised Immunity

Managing COVID-19 Patients with Renal Insufficiency, Multiple Comorbidities, or Compromised Immunity

Infectious DiseasesRespiratory MedicineInternal Medicine
A badge with ribbon in color black CME Unit: 1 point | An analog clock in color black 1 Hour | A black calendar with white triangle in center that has a black exclamation point in the middle 01 Jul 2025 

Overview

About this course

When your patient is hospitalised for COVID-19 but also has chronic kidney disease (CKD), how do you strike a balance between the risk of acute kidney injury and the benefits of remdesivir treatment?

How do you structure treatment plans in patients with multiple comorbidities while avoiding the potential hazards caused by adverse drug–drug interactions?

How do you manage COVID-19 infection and its rebound in immunocompromised patients, in the light of sparse research data?

Learning outcomes

Upon completion of this module, the participant will be able to:

  • Describe the impact of COVID-19 on patients with renal impairment
  • Identify the risks of remdesivir usage in patients with renal impairment
  • Define strategies to mitigate the risks associated with remdesivir treatment in COVID-19 patients with renal impairment
  • Compare treatment options available for high-risk COVID-19 patients
  • Specify contraindications for commonly used COVID-19 antivirals
  • Determine management techniques for COVID-19 rebound, specifically in immunocompromised patients

Topics covered

  • Current research findings on the use of remdesivir in COVID-19 patients with acute kidney injury
  • Recommendations for reducing risk in remdesivir treatment for patients with renal impairment
  • Drugs contraindicated to nirmatrelvir/ritonavir treatment
  • Results of early and extended remdesivir treatment in immunocompromised patients

1 CME Point Available

  • This module is accredited for 1 CME point for medical practitioners enrolled in the Medical Council of Hong Kong’s CME Programme for Practising Doctors who are not taking CME Programme for Specialists.
  • This module is accredited for 1 CME point for fellows of the Hong Kong College of Emergency Medicine, the Hong Kong College of Community Medicine, and the Hong Kong College of Physicians.
  • Please note that this module will not earn CME credit for fellows of colleges not listed here.
  • A certificate can be downloaded upon successful completion of the quiz. Please use the information on the certificate to claim your CME points.