MIMS Education

Manage HF step-by-step: clinical evidence behind NT-proBNP guidelines

Manage HF step-by-step: clinical evidence behind NT-proBNP guidelines

CardiologyInternal MedicineEmergency MedicineGeriatric Medicine
A badge with ribbon in color black CME Unit: 0.5/1 pts | An analog clock in color black 30 Minutes | A black calendar with white triangle in center that has a black exclamation point in the middle 30 Jan 2024 


About this course

While heart failure (HF) is a major healthcare problem in Hong Kong, stark differences have been observed in mortality and outcomes between patients with and without reductions in the cardiac biomarker N-terminal–pro hormone BNP (NT-proBNP).


In this module, we will:

  • Examine the science behind NT-proBNP synthesis
  • Review the studies that have led to NT-proBNP recommendation in major international guidelines
  • Discuss the optimal timing and prognostic value of NT-proBNP measurements to support patients at each stage of HF management

Learning outcomes

Upon completion of this module, participants should be able to:

  • Acknowledge the burden of HF and the advantages of early diagnosis
  • Rule out HF using evidence-based clinical cut-offs for NT-proBNP, including age-based cut-offs
  • Identify guideline recommendations for each stage of HF management, including acute and chronic AF, with the use of NT-proBNP
  • Describe the value of NT-proBNP in stratifying risk for patients with type 2 diabetes mellitus (T2DM)

Topics covered

  • Burden of HF in Hong Kong
  • Unmet clinical needs for HF management
  • Overview and international guidelines on NT-proBNP as an HF biomarker
  • Using NT-proBNP for HF diagnosis
  • Using NT-proBNP for in-hospital monitoring of HF
  • Using NT-proBNP for monitoring of chronic HF
  • HF risk stratification in patients with T2DM

CME point(s) available

  • This module is accredited for 1 CME Point for medical practitioners enrolled in The Medical Council of Hong Kong’s Continuing Medical Education Programme for Practising Doctors who are not taking CME for Specialists.
  • This module is accredited for 0.5 CME Point for fellows of the Hong Kong College of Physicians, Hong Kong College of Emergency Medicine and Hong Kong College of Pathologists.
  • Please note that this module will not earn CME credit for fellows of colleges not listed here.
  • A certificate can be downloaded upon successful completion of the quiz. Please use the information on the certificate to claim your CME points.