MIMS Education

Improving HPV screening and triage in light of vaccination

Improving HPV screening and triage in light of vaccination

Obstetrics And GynaecologyFamily MedicineGeneral Practice
A badge with ribbon in color black 0.5/1 pts | An analog clock in color black 1 Hour | A black calendar with white triangle in center that has a black exclamation point in the middle 07 Jun 2025 


About this course

Risk stratification of HPV-positive cases is changing in response to vaccination and clinical data. In this lecture, Dr Stoler and Dr Wright examine implications of the recent IMPACT trial (N=35,263) on primary HPV screening and triage, respectively. Speakers explain the background behind an updated algorithm using genotyping and dual staining to reduce the number of colposcopies undertaken by concentrating healthcare resources on clinically meaningful HPV-positive cases.

Learning outcomes

Upon completion of this module, participants will be able to:
  • Identify factors necessitating HPV screening of increased sensitivity.
  • Compare the risk of cervical disease in people screened HPV-negative or HPV-positive for HPV16/18 and 12 other HPVs.
  • Evaluate the performance of dual staining versus cytology in risk stratification of HPV-positive cases.
  • Explain the impact of shifting from cytology to dual staining on HPV management algorithms (including sensitivity, residual disease and number of colposcopies).

Topics covered

  • Sensitivity of HPV screening required given reduced disease prevalence
  • Risk stratification of HPV-positive cases: genotyping and cytology in clinical trials
  • Practical guidance for identifying clinically meaningful HPV-positive cases

Additional reading:

0.5/1 CME Point Available

  • This module is accredited for 1 CME Point for medical practitioners enrolled in The Medical Council of Hong Kong’s Continuing Medical Education Programme for Practising Doctors who are not taking CME for Specialists.
  • This module is accredited for 1 CME Point for fellows of the Hong Kong College of Emergency Medicine, Hong Kong College of Community Medicine, The Hong Kong College of Obstetricians and Gynaecologists, and The Hong Kong College of Pathologists; and 0.50 CME Point for fellows of the Hong Kong College of Physicians.
  • Please note that this module will not earn CME credit for fellows of colleges not listed here.
  • A certificate can be downloaded upon successful completion of the quiz. Please use the information on the certificate to claim your CME points.

Organised by:

Obstetrical and Gynaecological Society of Hong Kong
Hong Kong Society for Colposcopy and Cervical Pathology

Supported by: