About this course

The mRNA technology-based vaccines have played a pivotal role in the fight against COVID-19. Given the endemicity of COVID-19, it is essential to re-evaluate the potential role of vaccines and boosters in combating emerging SARS-CoV-2 variants considering the waning immunity. This e-learning module overviews the evolving threat of COVID-19 variants in light of the waning vaccine immunity, especially in at-risk populations, the unmet needs in vaccine development, and the safety and effectiveness of bivalent boosters.

Learning outcomes

• Understand the current utility of COVID-19 booster vaccinations
• Understand the mechanism of action of mRNA platform technology
• Identify the potential challenges associated with COVID-19 vaccine uptake
• Review the safety and effectiveness of bivalent COVID-19 mRNA vaccines
• Explore the next steps for continued protection as COVID-19 transitions into an endemic phase

Topics covered

• Mechanism of action of mRNA technology against respiratory pathogens
• Significance of booster vaccinations
• Global data on prevalence of new variants of concern
• Defence mechanisms against SARS-CoV-2 infections
• Identification of at-risk population for severe COVID-19
• Unmet needs and potential challenges associated with COVID-19 vaccination
• Risk of ‘long COVID’ and its association with vaccinations
• Safety and effectiveness of bivalent mRNA vaccine boosters
• Transitioning COVID-19 and evolving vaccination strategies

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