

Overview
The transition into menopause marks an important phase in a woman’s health journey. Many notice physical and emotional changes, while others experience a more gradual shift. These changes often begin in perimenopause, when hormonal fluctuations start to affect daily life. During this time, women may develop menopause symptoms that differ in pattern, intensity, and duration. This variation leads many to seek clarity on what is typical, what is concerning, and which management approaches may help.
Among the most common concerns are hot flashes. These episodes can interrupt sleep, affect concentration, and reduce overall quality of life. However, vasomotor changes represent only part of the picture. Many women also report mood changes, cognitive shifts, and genitourinary symptoms. These subtle signs reflect the evolving hormonal state seen in menopause.
Interest in treatment options continues to grow. Estrogen replacement is often part of the conversation, yet many questions remain. Who benefits most from hormonal therapy? When should treatment be considered? How do different formulations and routes influence outcomes? These questions highlight the need to understand both the underlying physiology and the principles that guide individualized care.
This module introduces the key concepts behind hormonal therapy in the menopause transition. It does not dive immediately into detailed regimens. Instead, it outlines the ideas that shape treatment decisions—how symptoms develop, when hormone-based options may be appropriate, and what factors influence patient selection. By keeping the discussion broad, the module invites learners to explore the nuances of hormonal therapy for menopause in greater depth as the course continues.
At the end of this learning module, participants should be able to:
Dr Lui, Man Wa, Ellen
Specialist in Obstetrics and Gynaecology
Accredited Certificate in Reproductive Medicine
Honorary Clinical Assistant Professor, The University of Hong Kong