MIMS Education

Acute Leukemia - Immunophenotyping

Acute Leukemia - Immunophenotyping

A badge with ribbon in color black Cat3B: 1 Point | An analog clock in color black 1 hour | A black calendar with white triangle in center that has a black exclamation point in the middle 27 Apr 2023 


About this course

Flow cytometry helps in diagnosis, lineage assignment, prognostication, and post-therapeutic monitoring of acute leukemia (AL). This e-learning module by Dr. Brent Wood elaborates on immunophenotypic changes that help identify abnormalities in maturation, a characteristic presentation of AL. Dr. Wood is currently Professor & Director of the Hematopathology Laboratory, Children’s Hospital, Los Angeles. He is well-known for his contribution to optimizing 9 and 10 color flow cytometry for identification of minimal residual disease in ALL and AML.

Learning outcomes

Upon completion of this module, you should be able to:
  • Understand the role of flow cytometry in the diagnosis of AL
  • Identify normal maturational patterns using flow cytometry
  • Enumerate and differentiate subtypes of AL by identifying the underlying immunophenotypic abnormalities

Topics covered

  • Diagnosis and classification of AL (blast enumeration and lineage assignment)
  • Presentation of different subtypes of AL
  • Differentiation between normal and neoplastic cell populations
  • Identification of immunophenotypic abnormalities

1 CME Point Available

A certificate can be downloaded upon successful completion of the quiz. Please use the information on the certificate to claim your CME points.

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